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Dr. Ananda Prasad: Comment #16

Comment #16

Total zinc levels in the prostate are 10 times higher than other soft tissues.  Zinc concentration in prostate-epithelial cancer cells are decreased.  We observed that in TRAMP mouse model, tumor weights were significantly higher when the dietary zinc intake was either deficient or high in comparison to normal zinc intake level, suggesting that an optimal dietary zinc intake may play a protective role against prostate cancer.  Further studies must be done in human to document the preventive effect of zinc on prostate cancer.

Ref.

Prasad, A.S., Mukhtar, H., Beck, F.W.J., Adhami, V.M., Siddiqui, I.A., Din, M., Hafeez, B.B., Kucuk, O.  Dietary zinc and prostate cancer in the Tramp Mouse model.  J Med Food, 13(1): 70-76, 2010.